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The generation, manipulation and quantification of non-classical light, such as quantum-entangled photon pairs, differs significantly from methods with classical light. Thus, quantum measures could be harnessed to give new information about the interaction of light with matter. In this study we investigate if quantum entanglement can be used to diagnose disease. In particular, we test whether brain tissue from subjects suffering from Alzheimer’s disease can be distinguished from healthy tissue. We find that this is indeed the case. Polarization-entangled photons traveling through brain tissue lose their entanglement via a decohering scattering interaction that gradually renders the light in a maximally mixed state. We found that in thin tissue samples (between 120 and 600 micrometers) photons decohere to a distinguishable lesser degree in samples with Alzheimer’s disease than in healthy-control ones. Thus, it seems feasible that quantum measures of entangled photons could be used as a means to identify brain samples with the neurodegenerative disease. 

Development of construction and materials standards serve technical, social and economic objectives. Most significantly, standards are required for the acceptance of materials by the engineering community. This paper contrasts the characteristics of codes and standards, and their development, for engineered materials and those for nonconventional and vernacular materials. Challenges associated with code and standard development for these materials are highlighted and discussed through case studies. Recommendations for approaches to codes and standards development for nonconventional and vernacular materials are presented. 

The ALICE Collaboration reports measurements of the large relative transverse momentum ( $k_T$) component of jet substructure in $pp$and Pb-Pb collisions at center-of-mass energy per nucleon pair $\sqrt{s_{\mathrm{NN}}}=5.02\mathrm{TeV}$. Enhancement in the yield of such large- $k_{\mathrm{T}}$emissions in head-on Pb-Pb collisions is predicted to arise from partonic scattering with quasiparticles of the quark-gluon plasma. The analysis utilizes charged-particle jets reconstructed by the anti- $k_{\mathrm{T}}$algorithm with resolution parameter $R=0.2$in the transverse-momentum interval $60<p_{\mathrm{T},\mathrm{ch},\mathrm{jet}}<80\mathrm{GeV}/c$. The soft drop and dynamical grooming algorithms are used to identify high transverse momentum splittings in the jet shower. Comparison of measurements in Pb-Pb and $pp$collisions shows medium-induced narrowing, corresponding to yield suppression of high- $k_T$splittings, in contrast to the expectation of yield enhancement due to quasiparticle scattering. The measurements are compared to theoretical model calculations incorporating jet modification due to jet-medium interactions (“jet quenching”), both with and without quasiparticle scattering effects. These measurements provide new insight into the underlying mechanisms and theoretical modeling of jet quenching. 

Abstract This paper presents a study of the inclusive forward J/ψyield as a function of forward charged-particle multiplicity in pp collisions at$$ \sqrt{s} $$ $\sqrt{s}$= 13 TeV using data collected by the ALICE experiment at the CERN LHC. The results are presented in terms of relativeJ/ψyields and relative charged-particle multiplicities with respect to these quantities obtained in inelastic collisions having at least one charged particle in the pseudorapidity range |η|<1. The J/ψmesons are reconstructed via their decay intoμ⁺μ⁻pairs in the forward rapidity region (2.5< y <4). The relative multiplicity is estimated in the forward pseudorapidity range which overlaps with the J/ψrapidity region. The results show a steeper-than-linear increase of the J/ψyields versus the multiplicity. They are compared with previous measurements and theoretical model calculations. 

Abstract Event-by-event fluctuations of the event-wise mean transverse momentum,$$\langle p_{\textrm{T}}\rangle $$ $⟨p_{\text{T}}⟩$, of charged particles produced in proton–proton (pp) collisions at$$\sqrt{s}$$ $\sqrt{s}$= 5.02 TeV, Xe–Xe collisions at$$\sqrt{s_{\textrm{NN}}}$$ $\sqrt{s_{\text{NN}}}$= 5.44 TeV, and Pb–Pb collisions at$$\sqrt{s_{\textrm{NN}}}$$ $\sqrt{s_{\text{NN}}}$= 5.02 TeV are studied using the ALICE detector based on the integral correlator$$\langle \!\langle \Delta p_\textrm{T}\Delta p_\textrm{T}\rangle \!\rangle $$ $⟨⟨\Delta p_{\text{T}}\Delta p_{\text{T}}⟩⟩$. The correlator strength is found to decrease monotonically with increasing produced charged-particle multiplicity measured at midrapidity in all three systems. In Xe–Xe and Pb–Pb collisions, the multiplicity dependence of the correlator deviates significantly from a simple power-law scaling as well as from the predictions of the HIJING and AMPT models. The observed deviation from power-law scaling is expected from transverse radial flow in semicentral to central Xe–Xe and Pb–Pb collisions. In pp collisions, the correlation strength is also studied by classifying the events based on the transverse spherocity,$$S_0$$ $S_0$, of the particle production at midrapidity, used as a proxy for the presence of a pronounced back-to-back jet topology. Low-spherocity (jetty) events feature a larger correlation strength than those with high spherocity (isotropic). The strength and multiplicity dependence of jetty and isotropic events are well reproduced by calculations with the PYTHIA 8 and EPOS LHC models. 

A<sc>bstract</sc> We report on the measurement of inclusive, non-prompt, and prompt J/ψ-hadron correlations by the ALICE Collaboration at the CERN Large Hadron Collider in pp collisions at a center-of-mass energy of 13 TeV. The correlations are studied at midrapidity (|y| <0.9) in the transverse momentum rangesp_T<40 GeV/cfor the J/ψand 0.15< p_T<10 GeV/cand |η|<0.9 for the associated hadrons. The measurement is based on minimum bias and high multiplicity data samples corresponding to integrated luminosities ofL_int= 34 nb⁻¹andL_int= 6.9 pb⁻¹, respectively. In addition, two more data samples are employed, requiring, on top of the minimum bias condition, a threshold on the tower energy ofE= 4 and 9 GeV in the ALICE electromagnetic calorimeters, which correspond to integrated luminosities ofL_int= 0.9 pb⁻¹andL_int= 8.4 pb⁻¹, respectively. The azimuthally integrated near and away side yields of associated charged hadrons per J/ψtrigger are presented as a function of the J/ψand associated hadron transverse momentum. The measurements are discussed in comparison to PYTHIA calculations. 

The production yields of the orbitally excited charm-strange mesons ${\mathrm{D}}_{\mathrm{s}1}\left(1^{+}\right)(2536{)}^{+}$and ${\mathrm{D}}_{\mathrm{s}2}^{*}\left(2^{+}\right)(2573{)}^{+}$were measured for the first time in proton-proton (pp) collisions at a center-of-mass energy of $\sqrt{s}=13\mathrm{TeV}$with the ALICE experiment at the LHC. The ${\mathrm{D}}_{\mathrm{s}1}^{+}$and ${\mathrm{D}}_{\mathrm{s}2}^{*+}$mesons were measured at midrapidity ( $\left|y\right|<0.5$) in minimum-bias and high-multiplicity pp collisions in the transverse-momentum interval $2<p_{\mathrm{T}}<24\mathrm{GeV}/c$. Their production yields relative to the ${\mathrm{D}}_{\mathrm{s}}^{+}$ground-state yield were found to be compatible between minimum-bias and high-multiplicity collisions, as well as with previous measurements in ${\mathrm{e}}^{\pm }\mathrm{p}$and ${\mathrm{e}}^{+}{\mathrm{e}}^{-}$collisions. The measured ${\mathrm{D}}_{\mathrm{s}1}^{+}/{\mathrm{D}}_{\mathrm{s}}^{+}$and ${\mathrm{D}}_{\mathrm{s}2}^{*+}/{\mathrm{D}}_{\mathrm{s}}^{+}$yield ratios are described by statistical hadronization models and can be used to tune the parameters governing the production of excited charm-strange hadrons in Monte Carlo generators, such as 8.